TRIM27 antibody

Catalog No. ABIN7126897

The Mouse Monoclonal anti-TRIM27 antibody (Clone PCRP-TRIM27-1B3) (ABIN7126897) specifically detects TRIM27 in IF and FACS. The antibody is reactive with Human samples.

Quick Overview for TRIM27 antibody (ABIN7126897)

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIM27 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-TRIM27-1B3

Product Details anti-TRIM27 Antibody

Purpose: TRIM27 Antibody

Specificity: Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.

Cross-Reactivity (Details): Human. Predicted to react with Mouse and Rat.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human TRIM27 protein

Isotype: IgG2a

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, U87 or Raji cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TRIM27

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Alternative Name: TRIM27

Background:

AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP

HeLa, U87 or Raji cells.

Molecular Weight: 58.49kDa

Gene ID: 5987, 440382

UniProt: P14373