Recombinant SHBG antibody

Catalog No. ABIN7126940

The Mouse Monoclonal anti-SHBG antibody (Clone rSHBG-4447) (ABIN7126940) specifically detects SHBG in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for Recombinant SHBG antibody (ABIN7126940)

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHBG antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: RSHBG-4447

Product Details anti-SHBG Antibody

Purpose: Recombinant Sex Hormone Binding Globulin (SHBG) Antibody

Specificity: Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human SHBG protein

Isotype: IgG2a, kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver, placenta or testis.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Alternative Name: SHBG

Background:

Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG)

Human liver, Placenta or Testis.

Molecular Weight: 45kDa

Gene ID: 6462, 632235

UniProt: P04278

Pathways: Hormone Transport