SMARCC1 antibody
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- Target See all SMARCC1 Antibodies
- SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SMARCC1 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- The SWI/SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF1 or SNF2i±) and Brg-1 (also designated SNF2 or SNF2i²) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
- Cross-Reactivity (Details)
- Human
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human SMARCC1 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product SMARCC1 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, K562 or Jurkat cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))
- Alternative Name
- SMARCC1 (SMARCC1 Products)
- Synonyms
- smarcc1 antibody, MGC53976 antibody, BAF155 antibody, CRACC1 antibody, Rsc8 antibody, SRG3 antibody, SWI3 antibody, AI115498 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 L homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 antibody, smarcc1.L antibody, smarcc1a antibody, SMARCC1 antibody, Smarcc1 antibody
- Background
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AI115498, BRG1-associated factor 155 (BAF155), Chromatin remodeling complex BAF155 subunit (CRACC1), Mammalian chromatin remodeling complex BRG1 associated factor 155, Rsc8, SRG3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1,SMARCC1 / BAF155
Cellular localisation: Nucleus. - Molecular Weight
- 123kDa
- Gene ID
- 6599, 476179
- UniProt
- Q92922
- Pathways
- Chromatin Binding
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