TSC22D1 antibody

Catalog No. ABIN7127120

The Mouse Monoclonal anti-TSC22D1 antibody (ABIN7127120) specifically detects TSC22D1 in WB, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for TSC22D1 antibody (ABIN7127120)

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSC22D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-TSC22D1 Antibody

Specificity: Transforming growth factor i²-stimulated acts as a transcriptional regulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGFi² pathway and also the PPARi³ signaling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human TSC22D1 protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for TSC22D1

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Alternative Name: TSC22D1

Background: Cerebral protein 2, Hucep2, KIAA1994, MGC17597, Regulatory protein TSC22, RP11 269C23.2, TGFB-stimulated clone 22 homolog, TGFB1I4, TGFbeta stimulated clone 22, Transcriptional regulator TSC 22, Transforming growth factor beta 1 induced transcript 4, Transforming growth factor beta 1 induced transcript 4 protein, TSC22D1,TSC22D1
Cellular localisation: Cytoplasm. Nucleus. Localized to nucleoplasm and nuclear bodies.

Molecular Weight: 16kDa

Gene ID: 8848, 436383

UniProt: Q15714