Recombinant Interleukin enhancer-binding factor 3 (ILF3) antibody
Quick Overview for Recombinant Interleukin enhancer-binding factor 3 (ILF3) antibody (ABIN7127571)
Target
See all Interleukin enhancer-binding factor 3 (ILF3) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human ILF3
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Interleukin enhancer-binding factor 3 (ILF3)
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Alternative Name
- ILF3
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Background
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Background: May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. The phosphorylated form at Thr-188 and Thr-315, in concert with EIF2AK2/PKR can inhibit vesicular stomatitis virus (VSV) replication (By similarity).
Aliases: Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80), ILF3, DRBF MPHOSPH4 NF90
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UniProt
- Q12906
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Pathways
- M Phase
Target
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