Recombinant DLG4 antibody

Catalog No. ABIN7127779

The Rabbit Monoclonal anti-DLG4 antibody (Clone 1H4) (ABIN7127779) specifically detects DLG4 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Recombinant DLG4 antibody (ABIN7127779)

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DLG4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1H4

Product Details anti-DLG4 Antibody

Purpose: DLG4 Recombinant Monoclonal Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PSD95

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Alternative Name: DLG4

Background:

Background: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Aliases: Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90), DLG4, PSD95

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity