ANAPC2 antibody
Quick Overview for ANAPC2 antibody (ABIN7128400)
Target
See all ANAPC2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of Human ANAPC2
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Isotype
- IgG
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Application Notes
- ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
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Alternative Name
- ANAPC2
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Background
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Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
Aliases: anapc2 antibody, Anaphase promoting complex subunit 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANC2_HUMAN antibody, APC2 antibody, Cyclosome subunit 2 antibody, KIAA1406 antibody, OTTHUMP00000022692 antibody, RP11 350O14.5 antibody
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UniProt
- Q9UJX6
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Pathways
- Regulation of Cell Size
Target
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