AGPAT2 antibody (AA 121-220)

Catalog No. ABIN708656

The Rabbit Polyclonal anti-AGPAT2 antibody is suitable to detect AGPAT2 in samples from Human. It has been validated for ELISA, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for AGPAT2 antibody (AA 121-220) (ABIN708656)

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGPAT2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AGPAT2 Antibody

Binding Specificity: AA 121-220

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Agpat2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AGPAT2

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Alternative Name: Agpat2

Background:

Synonyms: LPAAB, BSCL, BSCL1, EC 2.3.1.51, LPAAB, LPAAT beta, Lysophosphatidic acid acyltransferase beta, 1 acyl sn glycerol 3 phosphate acyltransferase beta, 1 acylglycerol 3 phosphate O acyltransferase 2, 1 AGP acyltransferase 2, 1 AGPAT2 antibody Berardinelli Seip congenital lipodystrophy.PLCB_HUMAN

Background: Agpat2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. It is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene ID: 10555