COQ3 antibody

Catalog No. ABIN7129340

This Rabbit Polyclonal antibody specifically detects COQ3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for COQ3 antibody (ABIN7129340)

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-COQ3 Antibody

Purpose: COQ3 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human EIF2AK3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for COQ3

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Alternative Name: COQ3

Background:

Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Aliases: COQ3 antibody, UG0215E05Ubiquinone biosynthesis O-methyltransferase antibody, mitochondrial antibody, 3-demethylubiquinol 3-O-methyltransferase antibody, EC 2.1.1.64 antibody, Polyprenyldihydroxybenzoate methyltransferase antibody, EC 2.1.1.114 antibody

UniProt: Q9NZJ6

Pathways: Methionine Biosynthetic Process