Cholesterol Esterase antibody (AA 151-180)

Catalog No. ABIN708806

The Rabbit Polyclonal anti-Cholesterol Esterase antibody has been validated for WB, ELISA, IHC (fro), IF (cc), IF (p) and IHC (p). It is suitable to detect Cholesterol Esterase in samples from Human.

Quick Overview for Cholesterol Esterase antibody (AA 151-180) (ABIN708806)

Target: Cholesterol Esterase (CEL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholesterol Esterase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cholesterol Esterase Antibody

Binding Specificity: AA 151-180

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bile salt-activated lipase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Cholesterol Esterase

Target: Cholesterol Esterase (CEL)

Alternative Name: Bile salt-activated lipase

Background:

Synonyms: BAL, Bile salt-stimulated lipase, BSDL, BSSL, Bucelipase, Carboxyl ester lipase bile salt stimulated lipase, Carboxyl ester lipase, CEase, CEL, CELL, Cholesterol esterase, FAP, FAPP, Fetoacinar pancreatic protein, LIPA, Lysophospholipase, pancreatic, MODY8. Pancreatic lysophospholipase, Sterol esterase antibody, CEL_HUMAN.

Background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq].

Gene ID: 1056

Pathways: Lipid Metabolism