SMAD1 antibody (pSer187)

Catalog No. ABIN7138458

The Rabbit Polyclonal anti-SMAD1 antibody has been validated for WB and ELISA. It is suitable to detect SMAD1 in samples from Human.

Quick Overview for SMAD1 antibody (pSer187) (ABIN7138458)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMAD1 Antibody

Binding Specificity: pSer187

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 187(P-H-S(p)-P-N) derived from Human Smad1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Alternative Name: SMAD1

Background:

Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Aliases: BSP-1 antibody, BSP1 antibody, HsMAD1 antibody, JV4-1 antibody, JV41 antibody, MAD homolog 1 antibody, MAD mothers against decapentaplegic homolog 1 antibody, Mad related protein 1 antibody, Mad-related protein 1 antibody, MADH1 antibody, MADR1 antibody, Mothers against decapentaplegic homolog 1 antibody, Mothers against DPP homolog 1 antibody, SMA- AND MAD-RELATED PROTEIN 1 antibody, SMAD 1 antibody, SMAD family member 1 antibody, SMAD mothers against DPP homolog 1 antibody, Smad1 antibody, SMAD1_HUMAN antibody, TGF beta signaling protein 1 antibody, Transforming growth factor-beta-signaling protein 1 antibody

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development