SYT1 antibody (pSer309)

Catalog No. ABIN7138543

This anti-SYT1 antibody is a Rabbit Polyclonal antibody detecting SYT1 in ELISA and IF. Suitable for Human.

Quick Overview for SYT1 antibody (pSer309) (ABIN7138543)

Target: SYT1 (Synaptotagmin I (SYT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-SYT1 Antibody

Binding Specificity: pSer309

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 309 (G-L-S(p)-D-P) derived from Human Synaptotagmin 1.

Isotype: IgG

Application Details

Application Notes: IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Alternative Name: SYT1

Background:

Background:

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11, 105(10):3992-7.
Cnops L, et al. Cereb Cortex. 2008 May, 18(5):1221-31.
Lynch KL, et al. Mol Biol Cell. 2007 Dec, 18(12):4957-68.

Aliases: DKFZp781D2042 antibody, FLJ42519 antibody, p65 antibody, SVP65 antibody, Synaptotagmin 2 antibody, Synaptotagmin I antibody, Synaptotagmin II antibody, Synaptotagmin-1 antibody, SYT antibody, Syt1 antibody, SYT1_HUMAN antibody, Syt2 antibody, SytI antibody

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport