MAP2K5 antibody (pSer311, pThr315)

Catalog No. ABIN7138546

This anti-MAP2K5 antibody is a Rabbit Polyclonal antibody detecting MAP2K5 in WB and ELISA. Suitable for Rat.

Quick Overview for MAP2K5 antibody (pSer311, pThr315) (ABIN7138546)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAP2K5 Antibody

Binding Specificity: pSer311, pThr315

Purpose: Phospho-Map2k5 (Ser311/Thr315) Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S(p)I-A-K-T(p)-Y-V) derived from Rat MEK5.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: Map2k5

Background:

Background: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

English J.M., Vanderbilt C.A., Xu S., Marcus S., Cobb M.H.J. Biol. Chem. 270:28897-28902(1995)

Aliases: Map2k5 antibody, Mek5 antibody, Mkk5 antibody, Prkmk5 antibody, Dual specificity mitogen-activated protein kinase kinase 5 antibody, MAP kinase kinase 5 antibody, MAPKK 5 antibody, EC 2.7.12.2 antibody, MAPK/ERK kinase 5 antibody, MEK 5 antibody

UniProt: Q62862

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway