CTNNB1 antibody (pSer33)

Catalog No. ABIN7138560

The Rabbit Polyclonal anti-CTNNB1 antibody is suitable to detect CTNNB1 in samples from Human. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CTNNB1 antibody (pSer33) (ABIN7138560)

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CTNNB1 Antibody

Binding Specificity: pSer33

Purpose: Phospho-CTNNB1 (Ser33) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 33 (L-D-S(p)-G-I) derived from Human b-Catenin.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CTNNB1

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Alternative Name: CTNNB1

Background:

Background: Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

Novak A, et al. (1998) Proc Natl Acad Sci U S A, 95(8): 4374-4379
Marin O, et al. (2003) Proc Natl Acad Sci U S A, 100(18): 10193-10200
Okamura H, et al. (2004) Mol Cell Biol, 24(10): 4184-4195
Xing Y, et al. (2003) Genes Dev, 17(22): 2753-2764
Barth AI, et al. (1999) Proc Natl Acad Sci U S A, 96(9): 4947-4952

Aliases: b-catenin antibody, Beta catenin antibody, Beta-catenin antibody, Cadherin associated protein antibody, Catenin (cadherin associated protein), beta 1, 88 kDa antibody, Catenin beta 1 antibody, Catenin beta-1 antibody, CATNB antibody, CHBCAT antibody, CTNB1_HUMAN antibody, CTNNB antibody, CTNNB1 antibody, DKFZp686D02253 antibody, FLJ25606 antibody, FLJ37923 antibody, OTTHUMP00000162082 antibody, OTTHUMP00000165222 antibody, OTTHUMP00000165223 antibody, OTTHUMP00000209288 antibody, OTTHUMP00000209289 antibody

UniProt: P35222

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2