CTBP1 antibody (pSer422)

Catalog No. ABIN7138613

This Rabbit Polyclonal antibody specifically detects CTBP1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for CTBP1 antibody (pSer422) (ABIN7138613)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CTBP1 Antibody

Binding Specificity: pSer422

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CTBP1

Background:

Background:

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: BARS antibody, brefeldin A- ribosylated substrate antibody, C terminal binding protein 1 antibody, C-terminal-binding protein 1 antibody, CTBP antibody, CtBP1 antibody, CTBP1_HUMAN antibody, MGC104684 antibody

UniProt: Q13363

Pathways: Retinoic Acid Receptor Signaling Pathway