Glycogen Synthase 1 antibody (pSer645)

Catalog No. ABIN7138673

This Rabbit Polyclonal antibody specifically detects Glycogen Synthase 1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Glycogen Synthase 1 antibody (pSer645) (ABIN7138673)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: pSer645

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 645 (P-P-S(p)-P-S) derived from Glycogen Synthase.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1

Background:

Background:

Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Jensen J, et al. (2012)Am J Physiol Endocrinol Metab 303, E82-9. Lin FC, et al. (2012) Am J Physiol Cell Physiol 302, C1539-47. Kelsall IR, et al. (2011)J Neurochem 118, 596-610.

Aliases: Glycogen [starch] synthase antibody, Glycogen synthase 1 (muscle) antibody, Glycogen synthase 1 antibody, GSY antibody, GYS antibody, Gys1 antibody, GYS1_HUMAN antibody, muscle antibody

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process