KRT8 antibody (pSer74)
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- Target See all KRT8 Antibodies
- KRT8 (Keratin 8 (KRT8))
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Binding Specificity
- pSer74
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KRT8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA
- Cross-Reactivity
- Human
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8).
- Isotype
- IgG
- Top Product
- Discover our top product KRT8 Primary Antibody
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anti-Keratin 8 (KRT8) antibody
KRT8 Reactivity: Human, Mouse WB, IHC, FACS, ICC, IHC (fro) Host: Mouse Monoclonal M20 unconjugated
anti-Keratin 8 (KRT8) (AA 92-393) antibodyKRT8 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Keratin 8 (KRT8) (Ser726), (Ser731) antibodyKRT8 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Keratin 8 (KRT8) (pSer432) antibodyKRT8 Reactivity: Human, Rat, Mouse WB, IF, IHC, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 Reactivity: Human, Rat, Zebrafish (Danio rerio) WB, IF, IHC, FACS, StM Host: Mouse Monoclonal H1 unconjugated
anti-Keratin 8 (KRT8) (AA 91-381) antibodyKRT8 Reactivity: Human, Rat, Monkey, Dog WB, IF, IHC, IHC (p) Host: Mouse Monoclonal 1B12 unconjugated
anti-Keratin 8 (KRT8) (AA 1-483) antibodyKRT8 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Keratin 8 (KRT8) (AA 391-483) antibodyKRT8 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 8A5D12 unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 Reactivity: Human, Cow, Pig, Rabbit, Sheep IF, IHC, FACS, StM Host: Mouse Monoclonal B22-1 unconjugated
anti-Keratin 8 (KRT8) (N-Term) antibodyKRT8 Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB:1:500-1:1000, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- KRT8 (Keratin 8 (KRT8))
- Alternative Name
- KRT8 (KRT8 Products)
- Background
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Background:
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Nakamichi I, et al. (2002) Mol Biol Cell, 13(10): 3441-3451.
Prochasson P, et al. (2002) Nucleic Acids Res, 30(15): 3312-3322.
Pankov R, et al. (1994) Proc Natl Acad Sci U S A, 91(3): 873-877.
Thorey IS, et al. (1993) Mol Cell Biol, 13(11): 6742-6751Aliases: CARD2 antibody, CK 8 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, CYKER antibody, Cytokeratin endo A antibody, Cytokeratin-8 antibody, DreK8 antibody, EndoA antibody, K2C8 antibody, K2C8_HUMAN antibody, K8 antibody, Keratin 8 antibody, Keratin type II cytoskeletal 8 antibody, Keratin, type II cytoskeletal 8 antibody, Keratin-8 antibody, KO antibody, Krt 2.8 antibody, KRT8 antibody, MGC118110 antibody, MGC174782 antibody, MGC53564 antibody, MGC85764 antibody, sb:cb186 antibody, Type-II keratin Kb8 antibody
- UniProt
- P05787
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