NOS1 antibody (pSer852)

Catalog No. ABIN7138716

The Rabbit Polyclonal anti-NOS1 antibody has been validated for WB and ELISA. It is suitable to detect NOS1 in samples from Human.

Quick Overview for NOS1 antibody (pSer852) (ABIN7138716)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NOS1 Antibody

Binding Specificity: pSer852

Purpose: Phospho-NOS1 (Ser852) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 852(F-N-S(p)-V-S) derived from Human n-NOS .

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Alternative Name: NOS1

Background:

Background:

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

Capettini LS, et al. (2011) DBr J Pharmacol 164, 1738-48
Ferreira JM, Burnett AL, Rameau GA (2011) J Neurosci 31, 1991-9
Chaudhury A, Rao YM, Goyal RK (2008) Am J Physiol Gastrointest Liver Physiol 295, G442-51

Aliases: 2310005C01Rik antibody, BNOS antibody, Constitutive NOS antibody, EC 1.14.13.39 antibody, IHPS 1 antibody, IHPS1 antibody, N-NOS antibody, NC-NOS antibody, neuronal Nitric Oxide Synthase antibody, Neuronal NOS antibody, Nitric oxide synthase , neuronal, included antibody, Nitric oxide synthase 1 (neuronal) antibody, Nitric oxide synthase 1 antibody, Nitric oxide synthase, brain antibody, Nitric oxide synthase, penile neuronal, included antibody, NNOS antibody, NO antibody, NOS 1 antibody, NOS antibody, NOS type I antibody, NOS-I antibody, NOS1 antibody, NOS1_HUMAN antibody, Peptidyl-cysteine S-nitrosylase NOS1 antibody

UniProt: P29475

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction