MKNK1 antibody (pThr255)

Catalog No. ABIN7138819

The Rabbit Polyclonal anti-MKNK1 antibody (ABIN7138819) specifically detects MKNK1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for MKNK1 antibody (pThr255) (ABIN7138819)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MKNK1 Antibody

Binding Specificity: pThr255

Purpose: Phospho-MKNK1 (Thr255) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 255 (L-T-T(p)-P-C) derived from Human MNK1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MKNK1

Background:

Background: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

Aliases: MAP kinase interacting kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase signal integrating kinase 1 antibody, MAP kinase signal-integrating kinase 1 antibody, MAP kinase-interacting serine/threonine-protein kinase 1 antibody, MAPK signal integrating kinase 1 antibody, MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody, mknk1 antibody, MKNK1_HUMAN antibody, MNK 1 antibody, Mnk1 antibody

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor