DPYSL2 antibody (pThr509)
Quick Overview for DPYSL2 antibody (pThr509) (ABIN7138863)
Target
See all DPYSL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr509
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogen
- Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2.
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Isotype
- IgG
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Application Notes
- WB:1:500-1:1000, IHC:1:50-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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Alternative Name
- DPYSL2
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Background
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Background:
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Miki Y., Science 266:66-71(1994).
Smith T.M., Genome Res. 6:1029-1049(1996).
Wilson C.A., Oncogene 14:1-16(1997).Aliases: Collapsin response mediator protein 2 antibody, Collapsin response mediator protein antibody, Collapsin response mediator protein hCRMP 2 antibody, CRAM antibody, CRMP 2 antibody, CRMP-2 antibody, CRMP2 antibody, DHPRP 2 antibody, DHPRP2 antibody, Dihydropyrimidinase 2 antibody, Dihydropyrimidinase like 2 antibody, Dihydropyrimidinase like 2 long form antibody, Dihydropyrimidinase related protein 2 antibody, Dihydropyrimidinase-related protein 2 antibody, DPYL 2 antibody, DPYL2 antibody, DPYL2_HUMAN antibody, DPYSL 2 antibody, Dpysl2 antibody, DRP-2 antibody, DRP2 antibody, Musunc 33 antibody, Musunc33 antibody, N2A3 antibody, TOAD 64 antibody, TOAD64 antibody, ULIP 2 protein antibody, ULIP-2 antibody, Ulip2 antibody, Unc-33-like phosphoprotein 2 antibody
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UniProt
- Q16555
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Pathways
- Regulation of Cell Size
Target
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