CASR antibody (pThr888)

Catalog No. ABIN7138884

The Rabbit Polyclonal anti-CASR antibody is suitable to detect CASR in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CASR antibody (pThr888) (ABIN7138884)

Target: CASR (Calcium-Sensing Receptor (CASR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CASR Antibody

Binding Specificity: pThr888

Purpose: Phospho-CASR (Thr888) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Threonine 888(R-A-T(p)-L-R) derived from Human Calcium Sensing Receptor.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CASR

Target: CASR (Calcium-Sensing Receptor (CASR))

Alternative Name: CASR

Background:

Background: Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Aliases: Ca sensing receptor antibody, Ca2+ sensing receptor 1 antibody, Ca2+ sensing receptor antibody, Calcium sensing receptor antibody, CAR antibody, CaSR antibody, CASR_HUMAN antibody, EIG8 antibody, Extracellular calcium sensing receptor antibody, Extracellular calcium sensing receptor [Precursor] antibody, Extracellular calcium-sensing receptor antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, Hypocalciuric hypercalcemia 1 antibody, Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody, MGC138441 antibody, NSHPT antibody, Parathyroid Ca(2+) sensing receptor 1 antibody, Parathyroid Cell calcium sensing receptor antibody, Parathyroid Cell calcium-sensing receptor antibody, PCAR 1 antibody, PCaR1 antibody

UniProt: P41180

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis