CSNK2A1/CK II alpha antibody (pSer362, pThr360)

Catalog No. ABIN7138896

The Rabbit Polyclonal anti-CSNK2A1/CK II alpha antibody has been validated for WB and ELISA. It is suitable to detect CSNK2A1/CK II alpha in samples from Human.

Quick Overview for CSNK2A1/CK II alpha antibody (pSer362, pThr360) (ABIN7138896)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CSNK2A1/CK II alpha Antibody

Binding Specificity: pSer362, pThr360

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name: CSNK2A1

Background:

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.

Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001)
Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)
Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)
Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)

Aliases: Casein kinase 2 alpha 1 polypeptide antibody, Casein kinase II alpha 1 antibody, Casein kinase II alpha 1 subunit antibody, Casein kinase II alpha subunit antibody, Casein kinase II subunit alpha antibody, CK II alpha antibody, CK II antibody, CK2 alpha antibody, CK2 catalytic subunit alpha antibody, CK2A1 antibody, CKII antibody, CKIIalpha antibody, CSK21_HUMAN antibody, CSNK2A1 antibody

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome