FLT1 antibody (pTyr1213)

Catalog No. ABIN7138921

This anti-FLT1 antibody is a Rabbit Polyclonal antibody detecting FLT1 in WB and ELISA. Suitable for Human.

Quick Overview for FLT1 antibody (pTyr1213) (ABIN7138921)

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FLT1 Antibody

Binding Specificity: pTyr1213

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Alternative Name: FLT1

Background:

Background:

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Raghu H, et al. (2012) Mol Oncol 6, 33-47
Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54
Ito N, Wernstedt C, Engstr?m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

Aliases: EC 2.7.10.1 antibody, FLT 1 antibody, FLT antibody, Flt-1 antibody, FLT1 antibody, Fms like tyrosine kinase 1 antibody, Fms related tyrosine kinase 1 antibody, Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody, Fms-like tyrosine kinase 1 antibody, FRT antibody, Soluble VEGF receptor 1 14 antibody, Soluble VEGFR1 variant 2 antibody, Soluble VEGFR1 variant 21 antibody, Tyrosine protein kinase FRT antibody, Tyrosine protein kinase receptor FLT antibody, Tyrosine-protein kinase FRT antibody, Tyrosine-protein kinase receptor FLT antibody, Vascular endothelial growth factor receptor 1 antibody, Vascular endothelial growth factor vascular permeability factor receptor antibody, Vascular permeability factor receptor 1 antibody, Vascular permeability factor receptor antibody, VEGFR 1 antibody, VEGFR-1 antibody, VEGFR1 antibody, VGFR1_HUMAN antibody

UniProt: P17948

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals