Claudin 7 antibody (pTyr210)

Catalog No. ABIN7138957

The Rabbit Polyclonal anti-Claudin 7 antibody (ABIN7138957) specifically detects Claudin 7 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Claudin 7 antibody (pTyr210) (ABIN7138957)

Target: Claudin 7 (CLDN7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Claudin 7 Antibody

Binding Specificity: pTyr210

Purpose: Phospho-CLDN7 (Tyr210) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y(p)-V) derived from Human Claudin 7.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Claudin 7

Target: Claudin 7 (CLDN7)

Alternative Name: CLDN7

Background:

Background:

Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells.

Keen T.J., Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: CEPTR L2 antibody, CEPTRL 2 antibody, CEPTRL2 antibody, Claudin 1 antibody, Claudin 7 antibody, Claudin 9 antibody, Claudin-7 antibody, Claudin1 antibody, Claudin7 antibody, Claudin9 antibody, CLD7_HUMAN antibody, CLDN 7 antibody, CLDN-7 antibody, CLDN7 antibody, Clostridium perfringens enterotoxin receptor like 2 antibody, CPETR L2 antibody, CPETRL 2 antibody, CPETRL2 antibody, Hs.84359 antibody

UniProt: O95471

Pathways: Hepatitis C