Ephrin B2 antibody (pTyr316)

Catalog No. ABIN7138977

The Rabbit Polyclonal anti-Ephrin B2 antibody has been validated for WB and ELISA. It is suitable to detect Ephrin B2 in samples from Human.

Quick Overview for Ephrin B2 antibody (pTyr316) (ABIN7138977)

Target: Ephrin B2 (EFNB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ephrin B2 Antibody

Binding Specificity: pTyr316

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin B2

Target: Ephrin B2 (EFNB2)

Alternative Name: EFNB2

Background:

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Chrencik JE,et al.( 2006) J Biol Chem,281(38):28185-28192.
Kertesz N, et al.( 2006) Blood,107(6):2330-2338.
Noren NK, et al.( 2004) Proc Natl Acad Sci USA,101(15):5583-5588

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation