APLP2 antibody (pTyr755)

Catalog No. ABIN7139061

The Rabbit Polyclonal anti-APLP2 antibody has been validated for ELISA and IHC. It is suitable to detect APLP2 in samples from Human.

Quick Overview for APLP2 antibody (pTyr755) (ABIN7139061)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-APLP2 Antibody

Binding Specificity: pTyr755

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) derived from Human APLP2.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2

Background:

Background:

APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box).

Sprecher C.A., Biochemistry 32:4481-4486(1993).
Wasco W., Nat. Genet. 5:95-99(1993).
von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).

Aliases: amyloid beta (A4) precursor like protein 2 antibody, Amyloid like protein 2 antibody, Amyloid precursor protein homolog HSD 2 antibody, amyloid precursor protein homolog HSD2 antibody, Amyloid protein homolog antibody, Amyloid-like protein 2 antibody, APLP-2 antibody, Aplp2 antibody, APLP2_HUMAN antibody, APPH antibody, APPL2 antibody, CDEBP antibody, CDEI box binding protein antibody, CDEI box-binding protein antibody

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour