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H2AFZ antibody (acLys7)

The Rabbit Polyclonal anti-H2AFZ antibody has been validated for WB, ELISA, IF, ICC, ChIP and IP. It is suitable to detect H2AFZ in samples from Human.
Catalog No. ABIN7139193

Quick Overview for H2AFZ antibody (acLys7) (ABIN7139193)

Target

See all H2AFZ Antibodies
H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity

  • 93
  • 33
  • 32
  • 5
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This H2AFZ antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)
  • Binding Specificity

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    acLys7

    Cross-Reactivity

    Human

    Purification

    Antigen Affinity Purified

    Immunogen

    Peptide sequence around site of Acetyl-Lys (7) derived from Human Histone H2A.Z

    Isotype

    IgG
  • Application Notes

    Recommended dilution: WB:1:200-1:2000, ICC:1:20-1:200, IF:1:20-1:200, IP:1:200-1:2000,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    H2AFZ (H2A Histone Family, Member Z (H2AFZ))

    Alternative Name

    H2AFZ

    Background

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

    Aliases: H2A histone family member Z antibody, H2A.z antibody, H2A/z antibody, H2afz antibody, H2AZ antibody, H2AZ_HUMAN antibody, Histone H2A.Z antibody, MGC117173 antibody

    UniProt

    P0C0S5

    Pathways

    Telomere Maintenance
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