LRP1 antibody (AA 3924-3942) (Biotin)

Catalog No. ABIN7140071

This Rabbit Polyclonal antibody specifically detects LRP1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for LRP1 antibody (AA 3924-3942) (Biotin) (ABIN7140071)

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-LRP1 Antibody (Biotin)

Binding Specificity: AA 3924-3942

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Peptide sequence from Human Prolow-density lipoprotein receptor-related protein 1 protein (3924-3942AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Alternative Name: LRP1

Background:

Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:11907044, PubMed:12888553, PubMed:12713657). Acts as an alpha-2-macroglobulin receptor (PubMed:26142438).

Aliases: A2MR antibody, Alpha 2 macroglobulin receptor antibody, alpha 2MR antibody, Alpha-2-macroglobulin receptor antibody, APOER antibody, Apolipoprotein E receptor antibody, APR antibody, CD 91 antibody, CD91 antibody, CD91 antigen antibody, IGFBP3R antibody, LDL receptor related protein 1 antibody, Low density lipoprotein receptor related protein 1 antibody, Low density lipoprotein related protein 1 antibody, Low-density lipoprotein receptor-related protein 1 intracellular domain antibody, LRP 1 antibody, LRP 515 antibody, LRP 85 antibody, LRP antibody, LRP ICD antibody, LRP-1 antibody, LRP-515 antibody, LRP-85 antibody, Lrp1 antibody, LRP1 protein antibody, LRP1_HUMAN antibody, LRP1A antibody, LRP515 antibody, LRP85 antibody, LRPICD antibody, MGC88725 antibody, Prolow density lipoprotein receptor related protein 1 antibody, TbetaR V/LRP 1/IGFBP 3 receptor antibody, TbetaRV/LRP1/IGFBP3 receptor antibody, TGFBR 5 antibody, TGFBR5 antibody, Type V tgf beta receptor antibody

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling