FYB antibody

Catalog No. ABIN7140321

Product Details anti-FYB Antibody

Target: FYB (FYN-Binding Protein (FYB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FYB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Cross-Reactivity: Human, Rat

Purification: Affinity purified

Immunogen: Purified recombinant human FYB protein fragments expressed in E.coli.

Isotype: IgG1, IgG1 kappa

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FYB

Target: FYB (FYN-Binding Protein (FYB))

Alternative Name: FYB (FYB Products)

Synonyms: fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody

Background:

Background: The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.

Aliases: ADAP, PRO0823, SLAP-130

UniProt: O15117

Pathways: TCR Signaling, Protein targeting to Nucleus