RAD23B antibody

Catalog No. ABIN7140325

This anti-RAD23B antibody is a Mouse Monoclonal antibody detecting RAD23B in WB, ELISA, IHC and ICC. Suitable for Human.

Quick Overview for RAD23B antibody (ABIN7140325)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD23B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-RAD23B Antibody

Cross-Reactivity: Hamster, Human, Monkey, Mouse, Rat

Purification: Affinity purified

Immunogen: Purified recombinant human hHR23b protein fragments expressed in E.coli.

Isotype: IgG2b

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,ICC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Alternative Name: RAD23B

Background:

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
 

Aliases: homolog of B; RAD23B; RD23B_HUMAN; UV excision repair protein RAD23 homolog B; XP C repair complementing complex 58 kDa; XP C repair complementing complex 58 kDa protein; XP C repair complementing protein; XP-C repair-complementing complex 58 kDa protein;

UniProt: P54727

Pathways: DNA Damage Repair