Cytokeratin 18 antibody

Catalog No. ABIN7140333

The Mouse Monoclonal anti-Cytokeratin 18 antibody has been validated for WB, ELISA and ICC. It is suitable to detect Cytokeratin 18 in samples from Human.

Quick Overview for Cytokeratin 18 antibody (ABIN7140333)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-Cytokeratin 18 Antibody

Cross-Reactivity: Human, Monkey

Purification: Affinity purified

Immunogen: Purified recombinant human KRT18 protein fragments expressed in E.coli.

Isotype: IgG2a

Application Details

Application Notes: Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide,0.1 mg/mLBSA and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: KRT18

Background:

Background: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Aliases: Cell proliferation-inducing gene 46 protein, Cytokeratin-18, Keratin-18, krt18,

UniProt: P05783

Pathways: Apoptosis, Caspase Cascade in Apoptosis