SUN1 antibody (AA 2-105) (Biotin)

Catalog No. ABIN7140582

Product Details anti-SUN1 Antibody (Biotin)

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Binding Specificity: AA 2-105

Reactivity: Arabidopsis thaliana

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUN1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Arabidopsis thaliana

Purification: >95%, Protein G purified

Immunogen: Recombinant Arabidopsis thaliana SUN domain-containing protein 1 protein (2-105AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUN1

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Alternative Name: SUN1 (SUN1 Products)

Synonyms: UNC84A antibody, 4632417G13Rik antibody, 5730434D03Rik antibody, Unc84a antibody, mKIAA0810 antibody, Sun domain-containing protein 1 antibody, Sad1 and UNC84 domain containing 1 antibody, sun-1 antibody, SUN1 antibody, Sun1 antibody

Background:

Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed: 24667841, PubMed: 25759303). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed: 21294795, PubMed: 25759303). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed: 22270916). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis (PubMed: 25412930). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed: 25759303).

Aliases: SUN1 antibody, At5g04990 antibody, MUG13.15 antibody, SUN domain-containing protein 1 antibody, AtSUN1 antibody

UniProt: Q9FF75

Pathways: Maintenance of Protein Location