RuvA antibody (AA 1-203) (FITC)
Quick Overview for RuvA antibody (AA 1-203) (FITC) (ABIN7141553)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-203
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Cross-Reactivity
- E. coli
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RuvA
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Background
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Background: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.
Aliases: ruvA antibody, b1861 antibody, JW1850 antibody, Holliday junction ATP-dependent DNA helicase RuvA antibody, EC 3.6.4.12 antibody
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UniProt
- P0A809
Target
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