RuvA antibody
Quick Overview for RuvA antibody (ABIN7833526)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- Anti-RuvA | Holliday junction ATP-dependent DNA helicase
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Cross-Reactivity (Details)
- Escherichia coli
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Immunogen
- Purified
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Application Notes
- 1 : 3000 (WB)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Serum. Contains 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 6 months, for longer storage-20°C is recommended, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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Expiry Date
- 6 months
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- RuvA
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Background
- RuvA protein of Escherichia coli binds specifically to the Holliday structure which is the intermediate of recombination at the late stage of homologous recombination and recombination repair, and forms a complex with RuvB motor protein, allowing the migration of Holliday junction using ATP hydrolysis energy and expands the heteroduplex region. In solution, it forms a tetramer and binds to the cross-like DNA of the Holliday junction from below and above, holding it in between
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Molecular Weight
- 22 kDa
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Gene ID
- 66674249
Target
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