PSMC5 antibody (Regulatory Subunit 8) (FITC)

Catalog No. ABIN7142240

This Rabbit Polyclonal antibody specifically detects PSMC5 in . It exhibits reactivity toward Human.

Quick Overview for PSMC5 antibody (Regulatory Subunit 8) (FITC) (ABIN7142240)

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC5 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-PSMC5 Antibody (FITC)

Binding Specificity: AA 253-324, Regulatory Subunit 8

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 26S proteasome regulatory subunit 8 protein (253-324AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Alternative Name: PSMC5

Background:

Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Aliases: 26S protease regulatory subunit 8 antibody, 26S proteasome AAA-ATPase subunit RPT6 antibody, Cim3 antibody, MSUG1 protein antibody, p45 antibody, p45/SUG antibody, Proteasome 26S ATPase subunit 5 antibody, Proteasome 26S subunit ATPase 5 antibody, Proteasome prosome macropain 26S subunit ATPase 5 antibody, Proteasome subunit p45 antibody, PRS8_HUMAN antibody, PSMC5 antibody, Rpt6 antibody, S8 antibody, SUG1 antibody, Tat binding protein homolog 10 antibody, TBP10 antibody, Thyroid hormone receptor interacting protein 1 antibody, Thyroid hormone receptor-interacting protein 1 antibody, Thyroid receptor interactor 1 antibody, TRIP1 antibody, TRIP1(SUG1) antibody

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway