HMGCR antibody (AA 588-887)

Catalog No. ABIN7142292

The Rabbit Polyclonal anti-HMGCR antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect HMGCR in samples from Human.

Quick Overview for HMGCR antibody (AA 588-887) (ABIN7142292)

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HMGCR Antibody

Binding Specificity: AA 588-887

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR

Background:

Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Aliases: 3 hydroxy 3 methylglutaryl CoA reductase antibody, 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody, 3 hydroxymethylglutaryl CoA reductase antibody, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody, 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody, 3H3M antibody, HMDH_HUMAN antibody, HMG CoA reductase antibody, HMG CoAR antibody, HMG-CoA reductase antibody, Hmgcr antibody, Hydroxymethylglutaryl CoA reductase antibody, LDLCQ3 antibody, MGC103269 antibody, Red antibody

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha