ASCL1 antibody (AA 1-236)

Catalog No. ABIN7142982

The Rabbit Polyclonal anti-ASCL1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ASCL1 in samples from Human.

Quick Overview for ASCL1 antibody (AA 1-236) (ABIN7142982)

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ASCL1 Antibody

Binding Specificity: AA 1-236

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Achaete-scute homolog 1 protein (1-236AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ASCL1

Target: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Alternative Name: ASCL1

Background:

Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5\\\'-CANNTG-3\\\'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

Aliases: Achaete scute complex homolog 1 antibody, Achaete scute complex homolog like 1 antibody, Achaete scute complex homologue 1 antibody, Achaete scute complex homologue like 1 antibody, Achaete scute complex like 1 antibody, Achaete scute family bHLH transcription factor 1 antibody, Achaete scute protein antibody, Achaete-scute homolog 1 antibody, Ascl 1 antibody, ascl1 antibody, ASCL1_HUMAN antibody, Ash 1 antibody, ASH-1 antibody, Ash1 antibody, bHLHa46 antibody, Class A basic helix-loop-helix protein 46 antibody, Hash 1 antibody, HASH1 antibody, Mammalian achaete scute homolog 1 antibody, Mammalian achaete scute homologue 1 antibody, Mash 1 antibody, Mash1 antibody

UniProt: P50553

Pathways: Dopaminergic Neurogenesis