ASIC3 antibody (AA 62-320)

Catalog No. ABIN7143004

Product Details anti-ASIC3 Antibody

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Binding Specificity: AA 62-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASIC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Acid-sensing ion channel 3 protein (62-320AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Alternative Name: ASIC3 (ACCN3 Products)

Synonyms: ACCN3 antibody, Accn3 antibody, DRASIC antibody, SLNAC1 antibody, TNaC1 antibody, AW742291 antibody, TNAC1 antibody, amiloride-sensitive cation channel 3 antibody, acid sensing ion channel subunit 3 antibody, acid-sensing (proton-gated) ion channel 3 antibody, ACCN3 antibody, ASIC3 antibody, Asic3 antibody

Background:

Background: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.

Aliases: ACCN 3 antibody, Accn3 antibody, ACCN3_HUMAN antibody, Acid sensing ion channel 3 antibody, Acid-sensing ion channel 3 antibody, Amiloride sensitive cation channel 3 antibody, Amiloride sensitive cation channel 3 testis antibody, Amiloride-sensitive cation channel 3 antibody, ASIC 3 antibody, ASIC3 antibody, DRASIC antibody, hASIC 3 antibody, hASIC3 antibody, hTNaC 1 antibody, hTNaC1 antibody, Modulatory subunit of ASIC 2a antibody, Modulatory subunit of ASIC2a antibody, Neuronal amiloride sensitive cation channel 3 antibody, Neuronal amiloride-sensitive cation channel 3 antibody, Proton gated cation channel subunit antibody, SLNAC 1 antibody, SLNAC1 antibody, Testis sodium channel 1 antibody, TNaC 1 antibody, TNaC1 antibody

UniProt: Q9UHC3