ADCY5 antibody (AA 584-719) (Biotin)

Catalog No. ABIN7143331

The Biotin-conjugated Rabbit Polyclonal anti-ADCY5 antibody (ABIN7143331) specifically detects ADCY5 in ELISA. The antibody is reactive with Human samples.

Quick Overview for ADCY5 antibody (AA 584-719) (Biotin) (ABIN7143331)

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY5 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-ADCY5 Antibody (Biotin)

Binding Specificity: AA 584-719

Purpose: ADCY5 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Adenylate cyclase type 5 protein (584-719AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ADCY5

Target: ADCY5 (Adenylate Cyclase 5 (ADCY5))

Alternative Name: ADCY5

Background:

Background: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642, PubMed:26206488, PubMed:24700542). Mediates signaling downstream of ADRB1 (PubMed:24700542). Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion (PubMed:24740569).

Aliases: AC 5 antibody, AC5 antibody, ADCY 5 antibody, Adcy5 antibody, ADCY5_HUMAN antibody, Adenylate cyclase type 5 antibody, Adenylate cyclase type V antibody, Adenylyl cyclase 5 antibody, ATP pyrophosphate lyase 5 antibody, ATP pyrophosphate-lyase 5 antibody

UniProt: O95622

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma