AKR7A2 antibody (AA 100-359)

Catalog No. ABIN7143586

This anti-AKR7A2 antibody is a Rabbit Polyclonal antibody detecting AKR7A2 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for AKR7A2 antibody (AA 100-359) (ABIN7143586)

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR7A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-AKR7A2 Antibody

Binding Specificity: AA 100-359

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Aflatoxin B1 aldehyde reductase member 2 protein (100-359AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Alternative Name: AKR7A2

Background:

Background: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Aliases: AFAR antibody, AFAR1 antibody, AFB1 aldehyde reductase 1 antibody, AFB1 AR1 antibody, AFB1-AR 1 antibody, AFB1AR1 antibody, Aflatoxin aldehyde reductase antibody, Aflatoxin B1 aldehyde reductase member 2 antibody, Aflatoxin beta1 aldehyde reductase antibody, Aiar antibody, AKR7 antibody, Akr7a2 antibody, Aldo keto reductase family 7 antibody, Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody, Aldo keto reductase family 7 member A2 antibody, Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody, Aldoketoreductase 7 antibody, ARK72_HUMAN antibody, SSA reductase antibody, Succinic semialdehyde reductase antibody

UniProt: O43488