AGRP antibody (AA 83-132)

Catalog No. ABIN7143593

Product Details anti-AGRP Antibody

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Binding Specificity: AA 83-132

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGRP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Agouti-related protein (83-132AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AGRP

Target: AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))

Alternative Name: AGRP (AGRP Products)

Synonyms: AGRT antibody, ART antibody, ASIP2 antibody, Agrt antibody, Art antibody, agouti related neuropeptide antibody, agouti-related protein pseudogene antibody, AGRP antibody, Agrp antibody, LOC100352591 antibody

Background:

Background: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.

Aliases: Agouti related neuropeptide antibody, Agouti Related Protein Homolog antibody, Agouti-related protein antibody, Agrp antibody, AGRP_HUMAN antibody, AGRT antibody, ART antibody, ASIP2 antibody

UniProt: O00253

Pathways: Feeding Behaviour, Photoperiodism