Angiopoietin 2 antibody (AA 19-485)

Catalog No. ABIN7144092

The Rabbit Polyclonal anti-Angiopoietin 2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Angiopoietin 2 in samples from Human.

Quick Overview for Angiopoietin 2 antibody (AA 19-485) (ABIN7144092)

Target: Angiopoietin 2 (ANGPT2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Angiopoietin 2 Antibody

Binding Specificity: AA 19-485

Purpose: ANGPT2 Antibody

Cross-Reactivity: Mouse, Rat

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Angiopoietin-2 protein (19-485AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Alternative Name: ANGPT2

Background:

Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Aliases: AGPT 2 antibody, Agpt2 antibody, ANG 2 antibody, ANG-2 antibody, ANG2 antibody, Angiopoietin 2a antibody, Angiopoietin 2B antibody, Angiopoietin-2 antibody, Angiopoietin2 antibody, ANGP2_HUMAN antibody, ANGPT 2 antibody, Angpt2 antibody, Tie2 ligand antibody

UniProt: O15123

Pathways: RTK Signaling