MEF2C antibody (pSer387) (HRP)

Catalog No. ABIN710210

The Rabbit Polyclonal anti-MEF2C antibody has been validated for WB and ELISA. It is suitable to detect MEF2C in samples from Mouse and Rat.

Quick Overview for MEF2C antibody (pSer387) (HRP) (ABIN710210)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-MEF2C Antibody (HRP)

Binding Specificity: pSer387

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEF2C around the phosphorylation site of Ser387

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background:

Synonyms: MEF2Cphospho S387, MADS box transcription enhancer factor 2 polypeptide C myocyte enhancer factor 2C, Myocyte enhancer factor 2C, Myocyte specic enhancer factor 2C, Similar to MADS box transcription enhancer factor 2 polypeptide C, MEF2C_HUMAN.

Background: MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.

Gene ID: 4208

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling