Apoptosis Inhibitor 5 antibody (AA 396-524) (Biotin)

Catalog No. ABIN7144452

The Rabbit Polyclonal anti-Apoptosis Inhibitor 5 antibody has been validated for ELISA. It is suitable to detect Apoptosis Inhibitor 5 in samples from Human.

Quick Overview for Apoptosis Inhibitor 5 antibody (AA 396-524) (Biotin) (ABIN7144452)

Target: Apoptosis Inhibitor 5 (API5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Apoptosis Inhibitor 5 Antibody (Biotin)

Binding Specificity: AA 396-524

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Apoptosis inhibitor 5 protein (396-524AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: API5

Background:

Background: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Aliases: AAC 11 antibody, AAC-11 antibody, AAC11 antibody, Antiapoptosis clone 11 protein antibody, API 5 antibody, API-5 antibody, api5 antibody, API5 like 1 antibody, API5_HUMAN antibody, API5L1 antibody, Apoptosis inhibitor 5 antibody, Cell migration inducing gene 8 protein antibody, Cell migration-inducing gene 8 protein antibody, Fibroblast growth factor 2 interacting factor 2 antibody, Fibroblast growth factor 2-interacting factor antibody, FIF antibody, MIG 8 antibody, MIG8 antibody, Migration inducing protein MIG8 antibody, Protein XAGL antibody

UniProt: Q9BZZ5

Pathways: Growth Factor Binding