Apoptosis Inhibitor 5 antibody

Catalog No. ABIN7073094

The Rabbit Polyclonal anti-Apoptosis Inhibitor 5 antibody is suitable to detect Apoptosis Inhibitor 5 in samples from Human, Mouse and Rat. It has been validated for IHC and IF.

Quick Overview for Apoptosis Inhibitor 5 antibody (ABIN7073094)

Target: Apoptosis Inhibitor 5 (API5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Apoptosis Inhibitor 5 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse FIF

Application Details

Application Notes: IHC/IF (H,M,R) 1:300-1:1000/1:400-1:2400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: FIF

Background: Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. API5 expression is often upregulated in tumor cells, particularly in metastatic cells. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Alternate Names: AAC 11, AAC11, Antiapoptosis clone 11 protein, API 5, API5, API5 like 1, API5L1, Cell migration inducing gene 8 protein, Fibroblast growth factor 2 interacting factor 2, FIF, MIG 8, MIG8, Migration inducing protein MIG8, Protein XAGL.

Gene ID: 11800

NCBI Accession: NP_031492

UniProt: O35841

Pathways: Growth Factor Binding