Aryl Hydrocarbon Receptor antibody (AA 126-353) (Biotin)

Catalog No. ABIN7144658

This Rabbit Polyclonal antibody specifically detects Aryl Hydrocarbon Receptor in ELISA. It exhibits reactivity toward Human.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 126-353) (Biotin) (ABIN7144658)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Aryl Hydrocarbon Receptor Antibody (Biotin)

Binding Specificity: AA 126-353

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AHR

Background:

Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Aliases: Ah receptor antibody, AhR antibody, AHR_HUMAN antibody, Aromatic hydrocarbon receptor antibody, Aryl hydrocarbon receptor antibody, Aryl hydrocarbon receptor precursor antibody, bHLHe76 antibody, Class E basic helix loop helix protein 76 antibody, Class E basic helix-loop-helix protein 76 antibody, HGNC:348 antibody

UniProt: P35869

Pathways: Regulation of Cell Size