ATXN7L3 antibody (AA 51-347) (Biotin)

Catalog No. ABIN7144806

Product Details anti-ATXN7L3 Antibody (Biotin)

Target: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Binding Specificity: AA 51-347

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATXN7L3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ataxin-7-like protein 3 protein (51-347AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATXN7L3

Target: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Alternative Name: ATXN7L3 (ATXN7L3 Products)

Synonyms: E030022H21Rik antibody, si:busm1-180g5.4 antibody, si:dz180g5.4 antibody, wu:fj12f07 antibody, zgc:136438 antibody, zgc:158566 antibody, ataxin 7 like 3 antibody, ataxin 7-like 3 antibody, ATXN7L3 antibody, Atxn7l3 antibody, atxn7l3 antibody

Background:

Background: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

Aliases: AT7L3_HUMAN antibody, Ataxin 7 like 3 antibody, Ataxin 7 like protein 3 antibody, Ataxin-7-like protein 3 antibody, atxn7l3 antibody, SAGA associated factor 11 homolog antibody, SAGA-associated factor 11 homolog antibody

UniProt: Q14CW9