BCOR antibody (AA 1569-1755)

Catalog No. ABIN7145322

The Rabbit Polyclonal anti-BCOR antibody has been validated for ELISA. It is suitable to detect BCOR in samples from Human.

Quick Overview for BCOR antibody (AA 1569-1755) (ABIN7145322)

Target: BCOR (BCL6 Co-Repressor (BCOR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCOR antibody is un-conjugated

Application: ELISA

Product Details anti-BCOR Antibody

Binding Specificity: AA 1569-1755

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human BCL-6 corepressor protein (1569-1755AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BCOR

Target: BCOR (BCL6 Co-Repressor (BCOR))

Alternative Name: BCOR

Background:

Background: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 \'Lys-4\' (H3K4me3) and \'Lys-36\' (H3K36me2).

Aliases: 5830466J11Rik antibody, 8430401K06Rik antibody, ANOP 2 antibody, ANOP2 antibody, BCL 6 co repressor antibody, BCL 6 corepressor antibody, BCL 6 interacting corepressor antibody, BCL-6 corepressor antibody, BCL6 co repressor antibody, BCL6 corepressor antibody, BCL6 interacting corepressor antibody, BCoR antibody, BCOR_HUMAN antibody, FLJ20285 antibody, FLJ38041 antibody, KIAA1575 antibody, MAA 2 antibody, MAA2 antibody, MCOPS 2 antibody, MCOPS2 antibody, MGC131961 antibody, MGC71031 antibody

UniProt: Q6W2J9