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ATG14 antibody (AA 1-492)

ATG14 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7145339
  • Target See all ATG14 Antibodies
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-492
    Reactivity
    • 46
    • 15
    • 8
    • 1
    Human
    Host
    • 38
    • 8
    Rabbit
    Clonality
    • 38
    • 8
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATG14 antibody is un-conjugated
    Application
    • 26
    • 21
    • 17
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)
    Isotype
    IgG
    Top Product
    Discover our top product ATG14 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    Alternative Name
    ATG14 (ATG14 Products)
    Synonyms
    ATG14L antibody, BARKOR antibody, KIAA0831 antibody, 4832427M01 antibody, Atg14L antibody, D14Ertd114e antibody, D14Ertd436e antibody, RGD1304610 antibody, autophagy related 14 antibody, ATG14 antibody, Atg14 antibody
    Background

    Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).

    Aliases: 4832427M01 antibody, ATG14 antibody, Atg14L antibody, Autophagy-related protein 14-like protein antibody, BAKOR_HUMAN antibody, Barkor antibody, Beclin 1-associated autophagy-related key regulator antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

    UniProt
    Q6ZNE5
    Pathways
    Autophagy
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