Klotho beta antibody (AA 1-130) (FITC)

Catalog No. ABIN7145517

The Rabbit Polyclonal anti-Klotho beta antibody has been validated for . It is suitable to detect Klotho beta in samples from Human.

Quick Overview for Klotho beta antibody (AA 1-130) (FITC) (ABIN7145517)

Target: Klotho beta (KLB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Klotho beta antibody is conjugated to FITC

Application: Please inquire

Product Details anti-Klotho beta Antibody (FITC)

Binding Specificity: AA 1-130

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Beta-klotho protein (1-130AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Klotho beta

Target: Klotho beta (KLB)

Alternative Name: KLB

Background:

Background: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).

Aliases: Beta-klotho antibody, BetaKlotho antibody, BKL antibody, KLB antibody, KLOTB_HUMAN antibody, Klotho beta like protein antibody, Klotho beta-like protein antibody

UniProt: Q86Z14

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding